Whether you’re searching for the answer to the question, “Does modafinil work for anxiety?” or want to know more about modafinil, you should know a few things. In this article, you will understand the side effects of modafinil and how it affects anxiety.
Cognitive effects of modafinil on several domains
Among other cognitive benefits, modafinil improves memory in the short term and executive function in sleep-deprived individuals. It may also improve the ability to plan and execute tasks. It may also have a positive effect on creativity.
Modafinil is a wakefulness promoter prescribed to treat narcolepsy, obstructive sleep apnea and shift action sleep disorder. It has a well-established safety profile. Some studies have reported minor adverse effects such as nausea and headache. However, modafinil is considered safe for most people.
The trial was conducted at Herlev Hospital in Denmark, and The study applicants were recruited from the Department of Neurology at the hospital. They gave written informed consent.
Participants were divided into two groups. One group received modafinil, and the other group received a placebo. The participants were given 200 mg capsules for seven weeks. They were asked to report adverse events at study visits.
Modafinil was given to participants daily in the morning. Participants were asked to complete questionnaires and neurocognitive tests. The modafinil group also performed significantly better on upper extremity function, cognitive flexibility, work and productivity, and energy. They made fewer errors on an episodic memory test.
Anxiolytic effects of modafinil
Whether or not modafinil produces anxiolytic effects in humans is not known. Modafinil has been used in clinical trials to treat sleep disorders, such as narcolepsy, and it has a reputation for being a mood-enhancing drug. However, it is not a stimulant, so it does not carry the classic amphetamine-like side effects.
Modafinil is a selective dopamine transporter inhibitor. It has a binding coefficient of about 4,000 nmol/L for the dopamine reuptake transporter. It also inhibits the reuptake of norepinephrine, a neurotransmitter involved in feelings, vigilance, and mental wakefulness.
In zebrafish, modafinil decreases anxiety-like behaviours. But it does not have anxiolytic effects on locomotion. It also determined that modafinil did not alter the time spent in the central zone. This zone is related to positive feelings and self-confidence.
There are reports of adverse effects associated with modafinil, including irritability and insomnia. However, most side effects subside after a few weeks without reducing the dose.
Side effects of modafinil
Using modafinil can cause long-term side effects. These side effects can lead to adverse health consequences. They can be severe. Those experiencing these side effects should see a doctor immediately.Several studies have looked at the side effects of modafinil. Some of these studies have been conducted in children, adolescents, adults, and narcoleptics. There are also studies looking at the pro-cognitive effects of modafinil. These studies have looked at cognitive dysfunction, as well as the effects of modafinil on anxiety and sleepiness.
Modafinil has been studied in both animals and humans and has been found to improve cognitive function. It is thought that its effects are related to its effect on adrenergic receptors. In addition, modafinil has been shown to increase the production of glutamate, orexin, and other neurotransmitters.Aside from the effects on sleepiness, modafinil has been shown to improve cognitive function in several animal models. In particular, modafinil has been shown to enhance working memory performance in mice.
The study aims to assess patients’ quality of life with DRES syndrome. The data collected were analyzed using the utility index and VAS score. The Medical and Health Research Ethics Committee granted the study and was ensured according to the Declaration of Helsinki. In the study, a total of 11 patients were included. Patients were informed of the study’s purpose and gave their consent. A smaller sample size is a study limitation, and future studies should be conducted using a more comprehensive questionnaire.
Author: Dr. Mark Edward Boersma, graduated from the Louisiana State University School of Medicine In Shreveport in 1993. He works in West Monroe, LA and 1 other location and specializes in Internal Medicine, Other Specialty and Hospital Medicine. Dr. Boersma is affiliated with Glenwood Regional Medical Center.